Review Case

1. What type of acid-base disturbance occurred in the Emergency Room?

2. What is the PA02?

3. What is the A-a gradient and what does it tell you?

4. Give at least two mechanisms of hypoxemia in this situation.

5. What does the elevated HCO3 tell you?

Spirometry revealed the following:
FEV1 at 0100=0.5 L (pred 2.9 L); at 0800=0.7 L.
FVC at 0100=Unobt. (pred 3.9 L); at 0800=1.7 L.

Hospital Course

Suggested Reading:

  1. Matthay, RA. Chronic Airway Diseases. Cecil Textbook of Medicine. 19th edition. WB Saunders Co, 1992, pp 386-394.
  2. Murray, JF. Respiratory Failure. Cecil Textbook of Medicine. 29th edition. WB Saunders Co, 1992, pp 452-459.
  3. Syllabus on COPD.

Last Updated: December 4, 1997
Created: March 14, 1996