Sensitivities and Specificities for Some Diagnostic Tests

Reference Target disorder 
(and gold standard)
Type of Patient Diagnostic data Sensitivity
PiD rate
TP rate
Specificity
Nill rate
TN rate
(28)
Ulcer, hiatus hernia,abnormal  mobility, or other important finding (by radiography) Patients referred for an upper gastrointestinal series History of ulcer, over age 50, pain relieved by food or milk, or pain after eating 95%
SnNOUT?
30%
(6) Alcohol dependency or abuse (by extensive clinical investigation) Medical and orthopedic inpatients Gama-glutamyl transpeptidase
Mean corpuscular volume
Liver function tests 
"Yes" to 1 or more of the 4 CAGE questions
"Yes" to 3 or more of the 4 CAGE questions
54%

63%
37%
85%

76%

64%
81%
81%

(27) Recovery with moderate to no disability (by follow-up) Patients with nontraumatic coma Corneal reflex 92% 35%
(26) Increased intracranial pressure(by lumbar puncture, surgery, or imaging) Patients and volunteers Absence of spontaneous  pulsation of the retinal  vein 100%
SnNout!
85%
(20)  
Iron deficiency anemia (by bone marrow aspiration) Consecutive hospital admissions >65 years old Red cell protoprophyrin
Mean red cell volume
Transferrin saturation
Serum ferritin
68%
72%
62%
82%
68%
68%
86%
90%
(23) Deep vein thrombosis (by venography) Patients with symptoms suggesting deep vein thrombosis One or both of impedance plethysmography and 125l-fibrinogen leg scanning 92% 92%
(17)   Pancreas cancer (by biopsy, surgery, or autopsy) Patients with symptoms or signs suggesting cancer of file pancreas Ultrasound (when successful)
CT scan
Endoscopic retrograde
  cholangio-pancretography (when successful)
70%
85%
95%
85%
90%
97%