Loyola University Medical Education Network

Cell Sequestration

Cell Sequestration involves radiolabeling and then heat damaging a small volume of the patient's red cells (usually 10 ml) to take advantage of the spleen's normal function, i.e., removal of damaged red cells. If the cells are radiolabeled properly, this procedure permits visualization of the spleen with minimal visualization of the liver. Rarely performed, it nevertheless is considered one of the classical mechanisms of localization of radiopharmaceuticals. The labeled damaged red cells have a moderately long tbiol, probably in the range of 10-20 hr.


Stephen Karesh, PhD.

Last Updated: August 14, 1996
Created: March 1, 1996