Loyola University Medical Education Network

BASIC CHEMISTRY OF Tc-99m RADIOPHARMACEUTICALS


Stannous Reduction Method

Pertechnetate is the oxidizing agent; stannous ion is the reducing agent. In the presence of a chelating agent (a compound with electronegative character that is capable of binding radiometal cations), the metal ion is tightly bound in the center of the octahedral structure

Other methods are useful in formation of Tc-99m compounds. In addition, special procedures are availkable for preparation of Tc-99m RBC's


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Stephen Karesh, PhD.

Last Updated: August 14, 1996
Created: March 1, 1996