Metastatic Brain Tumors
Multiple Metastatic Tumors to the Brain
40 year old lady with a history of breast carcinoma diagnosed six years ago, presented with headache and ataxia.
Imaging findings: Figure 1
Multiple metastases to the brain.
Metastatic tumors can be solitary or multiple.
Usually spherical and located at the gray-white matter junction.
Metastatic lesions are better identified by MRI than by CT. Metastatic lesions enhance with gadolinium.
Primary malignant tumors that spread (hematogenous) to the brain include: lung, breast, melanoma, thyroid and renal.
Solitary metastatic Tumor
67 year old woman status post right mastectomy for breast cancer, presents with severe headache.
Imaging findings: Figure 2
Solitary metastatic adenocarcinoma to the brain from breast primary.
Enhancing metastatic tumor is seen with sharply defined margins surrounded by edema in left frontal lobe.
Differential in an elderly patient is Glioblastoma which enhances inhomogenously with large areas of necrosis and irregular margins with finger like projections.
Metastasis is much more common than glioblastoma in adults.