Loyola University Medical Education Network Step 3 -
Dissection of the Cranial Cavity
  1. Using a sharp scalpel and rat-toothed forcep, very carefully peal away the dura from the middle cranial fossa. Be especially careful on the upper ridge of the petrous part of the temporal bone where CN V enters the dura. Try to follow cranial nerve V into the middle cranial fossa leaving the ganglion and its three branches intact as seen in this dissection.

  2. Removing the dura will expose the middle meningeal artery passing through the foramen spinosum, the trigeminal (semilunar) ganglion and its divisions such as the mandibular nerve exiting the foramen ovale and the maxillary nerve entering the foramen rotundum.

  3. Look for the greater petrosal nerve exiting its hiatus on the anterior surface of the petrous part of the temporal bone, but don't be disappointed if you don't see it.

  4. Now turn your attention to the internal carotid artery and peel the dura away from the cavernous sinus by following the internal carotid artery into the sinus where it is usually covered with dry venous blood. Inside the cavernous sinus see if you can find cranial nerve VI, which along with the internal carotid artery pass through the cavernous sinus. The ophthalamic nerve, the maxillary nerve and the oculomotor nerve (CN III) are located in the lateral wall of the cavernous sinus. Try to spare these nerves and follow them into the superior orbital fissure where they enter the orbit.


John A. McNulty, Ph.D.
Updated: Oct 8, 2008
Created: Jan 17, 1997