Loyola University Medical Education Network

Isotonicity, pH

The isotonicity of injectable drug products should be equal to that of a 0.9% NaCl solution, and the pH should approximate that of blood (pH 7.5). While intravenous injection of hypertonic or hypotonic solutions, or those with very low or very high pH, is not recommended, it is possible to inject compounds with these characteristics if done slowly.


Stephen Karesh, PhD.

Last Updated: August 14, 1996
Created: March 1, 1996